Population
Heterokaryons derived from polyethylene glycol-mediated fusion of chicken and rat myoblasts at different…
Comparison
Polyethylene glycol-mediated fusion of… vs Heterokaryons produced by fusion of…
Design
Preclinical
Follow-up
4-7 days of culture
Authors
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Dominant myoblast factors in heterokaryons caution against assuming stable myocyte phenotypes; leaves open relevance to cardiac regeneration models.
Regulatory factors maintaining myoblasts in a proliferating, undifferentiated state appear dominant over those governing differentiated gene expression when confronted in a common cytoplasm.
Konieczny et al. (1983) studied this question.
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