Key result
Among patients with left bundle branch block and initially preserved LVEF, 17% developed dyssynchrony cardiomyopathy (LVEF ≤40%) over a mean follow-up of 55 months.
Why the study?
In patients with LBBB whose LVEF is preserved during initial testing, the incidence of subsequent cardiomyopathy is not firmly established.
What is the risk of developing LV systolic dysfunction in patients with LBBB and initially preserved LVEF?
Cohort (n=216)
What is the risk of developing LV systolic dysfunction in patients with LBBB and initially preserved LVEF?
Patients with LBBB and initially preserved LVEF have a 17% risk of developing dyssynchrony cardiomyopathy, particularly those with baseline LVEF ≤60% and LVESD ≥ 2.9 cm, warranting serial imaging.
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May warrant serial imaging in LBBB with preserved LVEF; hypothesis-generating for targeted monitoring strategies.
Sharma et al. (2020) conducted a cohort in Left bundle branch block with preserved left ventricular ejection fraction (n=216). Left bundle branch block with preserved LVEF was evaluated on subsequent LV systolic dysfunction (LVEF ≤40%). Among patients with left bundle branch block and initially preserved LVEF, 17% developed dyssynchrony cardiomyopathy (LVEF ≤40%) over a mean follow-up of 55 months.
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