Impact of several proinflammatory and cell degradation factors in patients with aortic valve stenosis

Figures

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  Figure 1.. Serum CRP level in the control group and among patients with different degrees of aortic valve stenosis severity. CRP, C-reactive protein.

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  Figure 2.. Serum chemerin level in the control and aortic valve stenosis stenosis groups.

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  Figure 3.. Serum Chemerin level in the control group and in AoV stenosis groups with different grades of severity.

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  Figure 4.. Regression line of the serum chemerin level in connection with the AoV stenosis severity grade.

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  Figure 5.. Serum FGF-21 level in the control and AoV stenosis group.

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  Figure 6.. Serum FGF-21 expression level in the control group and in aortic valve stenosis groups with different grades of severity. FGF-21, fibroblast growth factor-21.

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  Figure 7.. Regression line of the serum FGF-21 level and the aortic valve stenosis severity grade. FGF-21, fibroblast growth factor-21.

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  Figure 8.. Regression analysis. Association analysis between serum chemerin and FGF-21, and chemerin and HDL (A) in the control and (B) in the AoV stenosis group. (C) Association between chemerin and MMP-9 in the AoV stenosis group. AoV, aortic valve; FGF-21, fibroblast growth factor-21; HDL, high-density lipoprotein.

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  Figure 9.. MMP-1 expression analysis. (A) Serum MMP-1 level in the control and AoV stenosis groups, ovals in green and red represent AoV stenosis patient clusters of data. (B) Histograms of MMP-1 distribution. Serum MMP-1 level. Modes are represented by color circles. (C) Serum MMP-1 levels in the control and AoV stenosis groups. Green ovals represent a cluster of 80% patients from (A) (D) MMP-1 serum level in control and in patients with different degrees of AoV severity. AoV, aortic valve; MMP-1, matrix metalloproteinase-1.

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  Figure 10.. Serum levels of MMP-3, MMP-9, TIMP-1 in the control and AoV stenosis groups. MMP, matrix metalloproteinase; TIMP, tissue inhibitor of metalloproteinase; AoV, aortic valve.

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  Figure 11.. Regression analyses. Regression lines of serum (A) MMP-1 and MMP-9, (B) MMP-1 and MMP-3, and (C) MMP-1 and TIMP-1 in patients with AoV stenosis. AoV, aortic valve; MMP, matrix metalloproteinase.