Key result
Hybrid procedures combining surgical valve repair or replacement with percutaneous coronary intervention offer a safe and effective alternative to traditional open surgery for concurrent disease.
Why the study?
Do hybrid procedures (surgical valve repair/replacement and PCI) improve safety and clinical outcomes in high-risk patients with concurrent CAD and valvular heart disease?
Do hybrid procedures (surgical valve repair/replacement and PCI) improve safety and clinical outcomes in high-risk patients with concurrent CAD and valvular heart disease?
Hybrid procedures combining surgical valve repair or replacement with PCI offer a safe, minimally invasive alternative to traditional open surgery for high-risk patients with concurrent coronary and valvular heart disease.
May support hybrid valve-PCI in high-risk patients; leaves open need for RCTs.
Concomitant coronary artery disease (CAD) and valvular heart disease is an increasingly common problem in the ageing population. Hybrid procedures combine surgical and transcatheter approaches to facilitate minimally invasive surgery or to transform a single high-risk open surgery into two less risky procedures. In ideal circumstances, this strategy may decrease the surgical risk in elderly, high-risk and reoperative surgical candidates, while improving patient comfort, convenience and cost-effectiveness. Hybrid procedures can be performed in a staged fashion or as a 'one-stop' procedure in a hybrid operating suite. Increasing evidence supports the safety and short-term efficacy of hybrid valve repair or replacement and coronary revascularisation procedures. Nevertheless, important questions remain, including the optimal timing of the individual procedures and the optimal antiplatelet therapy after percutaneous coronary intervention. With ongoing advances in procedural techniques and anticoagulation strategies, as well as the accumulation of long-term outcomes data, hybrid approaches to concomitant CAD and valvular heart disease will likely become increasingly common.
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Grubb et al. (2013) conducted a review in Concomitant coronary artery disease and valvular heart disease. Hybrid procedures (surgical valve repair/replacement and PCI) vs. Traditional open surgery (CABG and valve surgery) was evaluated. Hybrid procedures combining surgical valve repair or replacement with percutaneous coronary intervention offer a safe and effective alternative to traditional open surgery for concurrent disease.
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