Why the study?
Do the immunosuppressants cyclosporin (CsA) and FK506 prevent the development of cardiac hypertrophy in animal models?
Do the immunosuppressants cyclosporin (CsA) and FK506 prevent the development of cardiac hypertrophy in animal models?
Calcineurin inhibition with cyclosporin or FK506 prevents cardiac hypertrophy in animal models of intrinsic cardiomyopathy and pressure overload.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating in animal models; leaves open whether calcineurin inhibition prevents human cardiac hypertrophy.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Müller et al. (1998) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: