A high-speed bolus tagging method enables time-resolved velocity quantification of pulsatile flow within a single breath hold on conventional MR systems.
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Hypothesis-generating in animals; leaves open human translation and clinical validation of single-breath-hold flow imaging.
We have implemented a high speed method for cardiac-triggered blood velocity quantification within a single breath hold on a conventional MR system. The method, based on bolus tagging, was tested using a pulsatile flow phantom and evaluated in vivo. The image acquisition time was reduced by a factor of N by acquiring N phase encode lines per bolus tag application. The clarity of the flow tag was found to vary with how k-space was covered during data collection. The technique was optimized and multiple bolus tag images were obtained throughout the cardiac cycle within a single breathold.
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Chien et al. (1994) studied this question.
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