Key result
Thyroid hormones and their derivatives mediate adipose tissue remodeling by promoting thermogenesis and browning of white adipose tissue, offering potential therapeutic efficacy against obesity.
Why the study?
Aberrant adipose tissue remodeling in metabolic syndrome and obesity leads to metabolic disorders, prompting review of how thyroid hormones and their derivatives mediate adipose tissue activity and remodeling as potential therapeutic agents.
Thyroid hormones and their derivatives may offer therapeutic potential for obesity and metabolic disorders by promoting beneficial adipose tissue remodeling and thermogenesis.
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May support investigation of thyroid derivatives for obesity; leaves open clinical translation without trials.
Petito et al. (2023) conducted a review in Obesity and Metabolic Syndrome. Thyroid hormones and their derivatives was evaluated. Thyroid hormones and their derivatives mediate adipose tissue remodeling by promoting thermogenesis and browning of white adipose tissue, offering potential therapeutic efficacy against obesity.
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