Answers are grounded in this paper and cite their sources.
Demonstrates the in vivo functional importance of the actin-ABP 67 interaction and illustrates the use of suppressor analysis to identify physically interacting proteins.
The protein encoded by SAC6, a gene that can mutate to suppress a temperature-sensitive defect in the yeast actin gene, has been identified as a 67-kilodalton actin-binding protein (ABP 67) that associates with all identifiable actin structures. This finding demonstrates the in vivo functional importance of the actin-ABP 67 interaction previously established in vitro and illustrates the use of suppressor analysis to identify physically interacting proteins.
No takes yet. Share an insight, caveat, or question.
Adams et al. (1989) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: