Key result
Elevated CRP (>2.2 mg/l) was significantly associated with myocardial infarction (adjusted OR 1.42, p=0.032) and co-morbid MI and depression (adjusted OR 2.66, p=0.003), but not depression alone.
Why the study?
Is elevated high sensitive-CRP associated with depression, myocardial infarction, or both in a general population sample?
Cross-Sectional (n=9,258)
Is elevated high sensitive-CRP associated with depression, myocardial infarction, or both in a general population sample?
Odds Ratio: 2.66
p-value: p=0.003
Elevated CRP is independently associated with myocardial infarction and co-morbid MI and depression, but its association with depression alone is explained by confounding factors.
No takes yet. Share an insight, caveat, or question.
Elevated CRP warrants no depression screening change; leaves open inflammation's role in comorbid MI-depression.
Bjerkeset et al. (2010) conducted a cross-sectional in Depression and myocardial infarction (n=9,258). Elevated high sensitive-CRP (>2.2 mg/l) vs. Non-elevated CRP was evaluated on Co-morbid MI and depression (OR 2.66, p=0.003). Elevated CRP (>2.2 mg/l) was significantly associated with myocardial infarction (adjusted OR 1.42, p=0.032) and co-morbid MI and depression (adjusted OR 2.66, p=0.003), but not depression alone.
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