Key result
The presence of polyvascular disease in HFpEF patients was associated with a higher rate of cardiovascular events compared to those without PVD (44.0% vs 20.4%; HR 2.875, 95% CI 1.894-4.365, P<.001).
Why the study?
The prognostic significance of systemic atherothrombosis in heart failure with preserved ejection fraction remains unclear.
Does the presence of polyvascular disease predict cardiovascular events in patients with HFpEF?
Population
510 consecutive HFpEF patients
Comparison
Presence vs absence of polyvascular disease
Design
Prospective observational cohort study
Follow-up
Median 1430 days
Authors
Loading...
Polyvascular disease signals elevated CV risk in HFpEF; extends prognostic data but leaves open screening utility.
Cohort (n=510)
Does the presence of polyvascular disease predict cardiovascular events in patients with HFpEF?
Hazard Ratio: 2.875 (95% CI 1.894–4.365)
Absolute Event Rate: 44% vs 20.4%
p-value: p=<.001
The presence of polyvascular disease is a strong independent predictor of future cardiovascular events in patients with HFpEF, highlighting the importance of screening for systemic atherothrombosis in this population.
Fujisue et al. (2019) conducted a cohort in Heart failure with preserved ejection fraction (HFpEF) (n=510). Polyvascular disease (PVD) vs. Without polyvascular disease was evaluated on Cardiovascular events (HR 2.875, 95% CI 1.894-4.365, p=<.001). The presence of polyvascular disease in HFpEF patients was associated with a higher rate of cardiovascular events compared to those without PVD (44.0% vs 20.4%; HR 2.875, 95% CI 1.894-4.365, P<.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: