Key result
Therapeutic strategies like SERCA upregulation have a narrow therapeutic range, while regular exercise training appears to improve cardiac performance by normalizing myocardial physiology.
Why the study?
Do SERCA upregulation and regular exercise training improve cardiac performance in heart failure post-MI?
Population
Patients with heart failure as a result of a myocardial infarction (MI)
Design
Review
Authors
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Exercise training may normalize myocardial physiology in post-MI HF; leaves open the therapeutic window for SERCA upregulation.
Do SERCA upregulation and regular exercise training improve cardiac performance in heart failure post-MI?
This review highlights that while SERCA upregulation has a narrow therapeutic window, regular exercise training effectively normalizes myocardial physiology in post-MI heart failure.
Godfrey L. Smith (2007) conducted a review in Heart failure post-myocardial infarction. SERCA upregulation and regular exercise training was evaluated. Therapeutic strategies like SERCA upregulation have a narrow therapeutic range, while regular exercise training appears to improve cardiac performance by normalizing myocardial physiology.
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