Why the study?
Does intravenous sotalol cause myocardial depression or adverse hemodynamic effects in patients with heart disease and in dog models?
Population
20 patients with heart disease, as well as normal and catecholamine-depleted dogs.
Design
Other
Authors
Loading...
May support sotalol rate control without depression in heart disease; leaves open randomized confirmation before practice change.
Does intravenous sotalol cause myocardial depression or adverse hemodynamic effects in patients with heart disease and in dog models?
Intravenous sotalol safely reduces heart rate without causing intrinsic myocardial depression or adverse hemodynamic effects, even in patients with advanced chronic heart failure.
Brooks et al. (1970) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: