Key result
A simple ECG-based method for determining beat-to-beat variation during maximal respiration was reproducible and applicable as a clinical routine test for cardiac vagal neuropathy.
Why the study?
Does a simple ECG-based method for determining beat-to-beat variation during maximal respiration reliably assess cardiac vagal neuropathy in insulin-treated diabetics?
Cross-Sectional (n=176)
Does a simple ECG-based method for determining beat-to-beat variation during maximal respiration reliably assess cardiac vagal neuropathy in insulin-treated diabetics?
A simple ECG-based method measuring beat-to-beat variation during maximal respiration is a reproducible and applicable routine clinical test for cardiac vagal neuropathy in insulin-treated diabetics.
May support ECG screening for vagal neuropathy in diabetics; leaves open prospective validation before routine adoption.
The reproducibility of a simple method for determining the beat-to-beat variation during maximal respiration (duration of inspiration = duration of expiration = 5 sec), using an ordinary ECG apparatus and a ruler, was tested in 10 normals and 40 insulin-treated diabetics. The results were reproducible and beat-to-beat variation was found to be independent of a 25-minute period of rest. The method was subsequently applied to 126 insulin-treated diabetics and the results are in accordance with previous investigations on cardiac vagal neuropathy. The method is applicable as a clinical routine test for cardiac vagal neuropathy.
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Hilsted et al. (1979) conducted a cross-sectional in Juvenile diabetes (n=176). ECG-based beat-to-beat variation measurement during maximal respiration vs. Normal controls was evaluated on Reproducibility of beat-to-beat variation. A simple ECG-based method for determining beat-to-beat variation during maximal respiration was reproducible and applicable as a clinical routine test for cardiac vagal neuropathy.
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