Key result
Tissue-engineered living artificial heart valve alternatives represent a promising approach to overcome the drawbacks of conventional prostheses, though critical developmental challenges remain.
Design
Review
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Tissue-engineered valves should not yet change practice; leaves open optimization of durability and scalability for future trials.
Tissue engineering of living artificial heart valves represents a promising future alternative to conventional prostheses for treating heart valve disease.
Flanagan et al. (2003) conducted a review in Heart valve disease. Living artificial heart valve alternative (LAHVA) vs. Conventional prostheses was evaluated. Tissue-engineered living artificial heart valve alternatives represent a promising approach to overcome the drawbacks of conventional prostheses, though critical developmental challenges remain.
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