Key result
Patients with corrected atrioventricular septal defect had a lower presence of a distinct vortex ring core at E-peak compared to healthy controls.
Why the study?
Does corrected atrioventricular septal defect alter diastolic left ventricular inflow vortex ring formation compared to healthy controls?
Cross-Sectional (n=46)
No
Does corrected atrioventricular septal defect alter diastolic left ventricular inflow vortex ring formation compared to healthy controls?
The study aims to evaluate if altered inflow patterns in AVSD-corrected patients disturb normal vortex formation using 4DFlow MRI.
Answers are grounded in this paper and cite their sources.
Altered vortex formation may indicate diastolic inflow abnormalities in corrected AVSD; hypothesis-generating for functional implications.
Background Vortex formation in the left ventricle (LV) is suggested to contribute to efficient blood pumping and altered vortex formation is associated with diastolic dysfunction. Patients after atrioventricular septal defect (AVSD) correction present abnormalities in valve morphology and subsequently develop altered inflow patterns (Calkoen et al. JMRI 2014), which may disturb normal vortex formation. We aimed to analyze vortex ring formation in AVSD-corrected patients compared to healthy controls and to evaluate association with inflow angle.
No takes yet. Share an insight, caveat, or question.
Elbaz et al. (2015) conducted a cross-sectional in Corrected atrioventricular septal defect (AVSD) (n=46). Corrected atrioventricular septal defect vs. Healthy controls was evaluated on Presence of a distinct vortex ring core at E-peak (p=0.025). Patients with corrected atrioventricular septal defect had a lower presence of a distinct vortex ring core at E-peak compared to healthy controls.
Synapse has enriched 10 related papers. Consider them for comparative context: