Key result
Topical stimulation of the sympathetic vasodilator outflow area in conscious dogs caused a rise in blood pressure, tachycardia, and an atropine-reversible increase in hind limb blood flow.
Electrical stimulation of sympathetic vasodilator areas in conscious dogs produces marked circulatory responses (increased blood pressure, heart rate, and hind limb blood flow) without major behavioral reactions.
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No immediate clinical implications; leaves open translation of sympathetic cholinergic vasodilation to human cardiovascular regulation.
Bolme et al. (1967) studied Conscious dogs. Topical electrical stimulation of the sympathetic vasodilator outflow area in the hypothalamus and the mesencephalon was evaluated on Blood pressure, heart rate, blood flow to the hind limb and behaviour. Topical stimulation of the sympathetic vasodilator outflow area in conscious dogs caused a rise in blood pressure, tachycardia, and an atropine-reversible increase in hind limb blood flow.
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