Key result
This review highlights the relationship between childhood obesity, insulin sensitivity, body fat distribution, and the development of atherogenic dyslipidemia and early atherosclerosis.
Childhood obesity and associated dyslipidemia are key triggers for early atherosclerosis, highlighting the need for early cardiovascular risk assessment.
May support early CV risk evaluation in obese children; leaves open causal pathways for prospective trials.
Childhood obesity when associated with serum lipoprotein changes triggers atherosclerosis. Evidences suggest that the atherosclerotic process begins in childhood and that the extent of early atherosclerosis of the aorta and coronary arteries can be associated with lipoprotein levels and obesity. Furthermore, many studies in childhood demonstrate an important relationship between parameters of insulin sensitivity, body fat distribution, and the development of lipid abnormalities. This review focuses on the most recent findings on the relationship between obesity, dyslipidemia, and cardiovascular risk in children.
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D’Adamo et al. (2015) conducted a review in Obesity, dyslipidemia, and cardiovascular risk in children. Obesity and dyslipidemia was evaluated. This review highlights the relationship between childhood obesity, insulin sensitivity, body fat distribution, and the development of atherogenic dyslipidemia and early atherosclerosis.
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