Key result
Non-invasive evaluation using the parameter (Pd/ICT)/(AO/EO) may be used as an index for myocardial contractility by correcting for preload.
Why the study?
Can non-invasive parameters such as Pd/ICT and ET/PEP accurately evaluate myocardial contractility?
Observational
Can non-invasive parameters such as Pd/ICT and ET/PEP accurately evaluate myocardial contractility?
The non-invasive parameter (Pd/ICT)/(AO/EO) may serve as a useful index for evaluating myocardial contractility by correcting for preload.
Answers are grounded in this paper and cite their sources.
May support non-invasive contractility assessment correcting for preload; leaves open prospective validation before clinical use.
In evaluation of cardiac function by the non-invasive method, the possibility of separation of cardiac muscle performance from cardiac pump performance was studied. Among the non-invasive values, SV/ET, SV/(AO/EO), Pd/ICT, Pd/PEP, 1/ICT2, ET/PEP, and ET/ICT were considered as parameters for myocardial contractility. This research especially focused on Pd/ICT and ET/PEP. In auricular fibrillation it was possible to draw Starling-like curves and 3 dimensional coordinates to estimate a Vmax-like value. However this method could not be used in sinus rhythm. Whereas, in hypertension with abnormal afterload and uremia with abnormal preload, myocardial contractility was expressed by Pd/ICT under the influence of almost pure preload and ET/PEP under the influence of both preload and afterload. Therefore Pd/ICT was corrected with preload (AO/EO) and (Pd/ICT)/(AO/EO) may be used as the index for myocardial contractility.
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Kikawada et al. (1975) conducted an observational in Cardiac function evaluation (auricular fibrillation, hypertension, uremia). Non-invasive evaluation parameters (Pd/ICT and ET/PEP) was evaluated on Myocardial contractility. Non-invasive evaluation using the parameter (Pd/ICT)/(AO/EO) may be used as an index for myocardial contractility by correcting for preload.
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