Key result
Intravenous heparin dosage was significantly correlated to thrombus resolution in patients with deep venous thrombosis.
Why the study?
Does intravenous heparin infusion improve thrombus resolution in patients with deep venous thrombosis?
Population
280 patients with phlebographically proven deep venous thrombosis
Design
Cohort
Follow-up
one week
Authors
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May support dose-dependent resolution with IV heparin in DVT; hypothesis-generating and requires RCT confirmation before practice change.
Observational (n=280)
Does intravenous heparin infusion improve thrombus resolution in patients with deep venous thrombosis?
Intravenous heparin for DVT results in partial or complete thrombus clearance in 39% of patients at one week, with resolution significantly correlated to heparin dosage.
Holm et al. (1984) conducted an observational in Deep Venous Thrombosis (n=280). Intravenous heparin infusion was evaluated on Thrombus resolution on control phlebography after one week. Intravenous heparin dosage was significantly correlated to thrombus resolution in patients with deep venous thrombosis.
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