Key result
Excess body weight in patients with acute coronary syndrome was associated with higher risk profile characteristics without an increase in hospital mortality or cardiovascular events.
Why the study?
Does excess body weight affect in-hospital mortality and cardiovascular events in Middle Eastern patients presenting with acute coronary syndrome?
Observational (n=7,843)
Yes
Does excess body weight affect in-hospital mortality and cardiovascular events in Middle Eastern patients presenting with acute coronary syndrome?
Excess body weight in Middle Eastern patients with ACS is associated with a higher baseline risk profile but does not increase in-hospital mortality or major cardiovascular events.
Suggests no short-term outcome penalty from excess weight in Middle Eastern ACS; extends obesity paradox observations but leaves open causal and long-term questions.
We evaluated the effect of body weight on the outcome of Middle Eastern patients presenting with acute coronary syndrome (ACS). Analysis of the Gulf Registry of Acute Coronary Events (Gulf RACE) survey that included 7843 consecutive patients hospitalized with ACS was made. Patients were categorized as normal weight, overweight, or obese based on their body mass index (BMI). Overall, 67% of patients were overweight or obese; obese and overweight patients were more likely to be female and have diabetes mellitus, hypertension, dyslipidemia, and less likely to be smokers. In-hospital mortality, congestive heart failure, cardiogenic shock, and strokes were comparable between the groups, although patients with obesity were more likely to have recurrent ischemia and major bleeding complication in the ST-elevation myocardial infarction group. Excess body weight with ACS is associated with higher risk profile characteristics without an increase in hospital mortality or cardiovascular events.
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Hadi et al. (2009) conducted an observational in Acute coronary syndrome (n=7,843). Excess body weight (overweight or obese) vs. Normal weight was evaluated on In-hospital mortality, congestive heart failure, cardiogenic shock, and strokes. Excess body weight in patients with acute coronary syndrome was associated with higher risk profile characteristics without an increase in hospital mortality or cardiovascular events.
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