What question did this study set out to answer?

This research aims to determine how angiotensin II affects protein synthesis and cell growth in embryonic chick heart cells.

August 1, 1990AJP Heart and Circulatory Physiology

Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells

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Authors

KBKenneth M. BakerTexas A&M Health Science Center JAJoseph F. AcetoNew York Law School

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Implication

Randomized trial investigates the effects of angiotensin II on protein synthesis and growth in chick myocytes, indicating its potential role in cardiac development.

Key Points

This research aims to determine how angiotensin II affects protein synthesis and cell growth in embryonic chick heart cells.
Cultured embryonic chick myocytes were exposed to angiotensin II for various durations.
Protein synthesis and total cellular protein levels were measured at 120, 144, and 168 hours post-exposure.
Effects of angiotensin II antagonist and hexapeptide were also assessed.
Angiotensin II increased total cellular protein by 32% compared to control (0.0119 +/- 0.0008 h-1 vs 0.0090 +/- 0.0003 h-1).
Total RNA levels in myocytes rose significantly at 12 hours post-angiotensin II exposure.
Inhibitory effects of ANG II antagonist on protein synthesis indicate the critical role of angiotensin II.

Cite This Study

Baker et al. (1990) studied this question.

synapsesocial.com/papers/6a224dfe42d97c116a7fc7af https://doi.org/10.1152/ajpheart.1990.259.2.h610

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Implication

Randomized trial investigates the effects of angiotensin II on protein synthesis and growth in chick myocytes, indicating its potential role in cardiac development.

Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells

Discussion

Member takes

Implication

Key Points

Cite This Study

Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells

Discussion

Member takes

Implication

Key Points

Cite This Study

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