Mean sleeping systolic blood pressure <105 mmHg was associated with a 7.6-fold higher likelihood of death compared to ≥105 mmHg in advanced heart failure (OR 7.61; 95% CI 1.56-3704; p=0.01).
Observational (n=38)
Do 24-hour ambulatory blood pressure monitoring parameters predict survival in patients with NYHA class IV congestive heart failure?
In patients with NYHA class IV heart failure, lower systolic blood pressure (<105 mmHg) on 24-hour ambulatory monitoring is a strong independent predictor of mortality.
Odds Ratio: 7.61 (95% CI 1.56–3704)
p-value: p=0.01
OBJECTIVE: To evaluate the relationship between 24-hour ambulatory arterial blood pressure monitoring and the prognosis of patients with advanced congestive heart failure. METHODS: We studied 38 patients with NYHA functional class IV congestive heart failure, and analyzed left ventricular ejection fraction, diastolic diameter, and ambulatory blood pressure monitoring data. RESULTS: Twelve deaths occurred. Left ventricular ejection fraction (35.2 +/-7.3%) and diastolic diameter (72.2 +/- 7.8mm) were not correlated with the survival. The mean 24-hour (SBP24), waking (SBPw), and sleeping (SBPs) systolic pressures of the living patients were higher than those of the deceased patients and were significant for predicting survival. Patients with mean SBP24, SBPv, and SBPs >/=105mmHg had longer survival (p=0.002, p=0.01 and p=0.0007, respectively). Patients with diastolic blood pressure sleep decrements (dip) and patients with mean blood pressure dip /= 105 mmHg CONCLUSION: Ambulatory blood pressure monitoring appears to be a useful method for evaluating patients with congestive heart failure.
Canesin et al. (Tue,) conducted a observational in advanced congestive heart failure (n=38). Mean sleeping systolic blood pressure <105 mmHg vs. Mean sleeping systolic blood pressure ≥105 mmHg was evaluated on Survival (OR 7.61, 95% CI 1.56-3704, p=0.01). Mean sleeping systolic blood pressure <105 mmHg was associated with a 7.6-fold higher likelihood of death compared to ≥105 mmHg in advanced heart failure (OR 7.61; 95% CI 1.56-3704; p=0.01).