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June 16, 2016International PsychogeriatricsOpen Access

Depression risk in patients with heart failure in primary care practices in Germany

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Key result

Heart failure was associated with a significantly higher risk of diagnosed depression at 5 years compared to matched controls without heart failure (28.9% vs 18.2%; p<0.001).

Why the study?

Does heart failure increase the risk of diagnosed depression in primary care patients?

Population

132,994 patients between 40 and 90 years of age from 1,072 primary care practices in Germany, consisting of…

Comparison

Heart failure (exposure) vs Matched controls without heart failure

Design

Cohort

Follow-up

up to 5 years

Authors

MKMarcel KonradFOM University of Applied Sciences for Economics and ManagementJBJens BohlkenKlinik für SchlafmedizinMRMichael A. RappUniversity of Potsdam

Discussion

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Implication

May warrant depression monitoring in primary care HF patients; hypothesis-generating and requires prospective trials for causality.

Study Design

Type

Cohort (n=132,994)

Multicenter

Yes

Structured PICO

Does heart failure increase the risk of diagnosed depression in primary care patients?

P
Population
132,994 patients aged 40 to 90 years from 1,072 primary care practices in Germany, comprising 66,497 with heart failure and 66,497 matched controls, followed for up to 5 years.
E
Exposure
Heart failure (exposure)
C
Comparator
Matched controls without heart failure (matched 1:1 on age, sex, health insurance, past depression diagnosis, and follow-up duration)
O
Outcome
Diagnosed depression

Main Result

Absolute Event Rate: 28.9% vs 18.2%

p-value: p=<0.001

Patients with heart failure have a significantly higher risk of developing diagnosed depression compared to matched controls in a primary care setting.

Cite This Study

Konrad et al. (2016) conducted a cohort in Heart failure (n=132,994). Heart failure vs. Matched controls without heart failure was evaluated on Diagnosed depression at 5 years (p=<0.001). Heart failure was associated with a significantly higher risk of diagnosed depression at 5 years compared to matched controls without heart failure (28.9% vs 18.2%; p<0.001).

synapsesocial.com/papers/6a2254f285ab2fb30c450108https://doi.org/10.1017/s1041610216000867

Topics

Heart failureHFrEF treatment
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