Key result
Atenolol resolves a novel T wave and QRS alternans pattern in a pediatric LQT3 case.
Why the study?
To report a previously undescribed ECG pattern combining T wave alternans and QRS alternans in a patient with long QT syndrome.
Does atenolol resolve the combined T wave and QRS alternans pattern in a patient with LQT3?
Population
One 6-year-old girl with long QT syndrome
Design
Case report
Follow-up
2 months
Authors
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Case report of atenolol-responsive alternans in LQT3 should not change practice; extends ECG phenotype and leaves open efficacy questions.
Case Report (n=1)
Does atenolol resolve the combined T wave and QRS alternans pattern in a patient with LQT3?
Combined T wave and QRS alternans is a newly described ECG pattern in LQT3 that may increase cardiac event risk and appears responsive to atenolol.
Макаров et al. (2024) conducted a case report in Long QT syndrome (LQT3) (n=1). Atenolol was evaluated on Presence of combined T wave alternans and QRS alternans (AT/AQRS). In a 6-year-old girl with LQT3, a novel ECG pattern of combined T wave and QRS alternans during night sleep resolved after 2 months of treatment with atenolol 1 mg/kg.
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