Population
BALB/c mice, BALB/c mice lacking the invariant J alpha 281 gene, BALB/c CD1d mice, and in vitro neonatal…
Comparison
Infection with myocarditic variant of… vs Infection with nonmyocarditic variant of CVB3…
Design
Preclinical
Authors
Loading...
Hypothesis-generating for CD1d-targeted therapy in viral myocarditis; human relevance untested.
CD1d expression on cardiac myocytes is essential for the pathogenicity of Coxsackievirus B3-induced myocarditis, mediating cytotoxicity via V gamma 4(+) T cells.
Huber et al. (2003) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: