Why the study?
Is parvovirus B19 infection associated with myocarditis and cardiac allograft rejection in children?
Population
810 children, including those with suspected myocarditis, cardiac transplant rejection, and control subjects.
Comparison
Polymerase chain reaction analysis of myocardial… vs Control subjects (n=250)
Design
Cross-sectional
Authors
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Parvovirus B19 PCR may identify rare etiologies in pediatric myocarditis or rejection; leaves open causality and management implications.
Is parvovirus B19 infection associated with myocarditis and cardiac allograft rejection in children?
Parvovirus B19 is associated with a small percentage of pediatric myocarditis and cardiac transplant rejection cases, and PCR provides a rapid diagnostic method.
Schowengerdt et al. (1997) studied this question.
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