Why the study?
Does Angiotensin Converting Enzyme density and activity differ across different rat vascular beds?
Population
Rats (vascular beds including mesenteric resistance arteries, brain microvessels, and aorta)
Comparison
Measurement of Angiotensin Converting Enzyme… vs Comparison across different vascular beds
Design
Preclinical
Authors
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Vascular ACE distribution varies in rats; leaves open whether this affects regional inhibitor responses in humans.
Does Angiotensin Converting Enzyme density and activity differ across different rat vascular beds?
ACE is unevenly distributed in the rat vascular tree, with higher density in mesenteric resistance arteries, but its catalytic characteristics remain consistent across different beds.
Jandeleit‐Dahm et al. (1995) studied this question.
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