Why the study?
Does administration of pro ANF 31-67 and ANF 99-126 improve diuresis and natriuresis in conscious non-human primates?
Population
Conscious non-human primates (Macaca fascicularis)
Design
Preclinical
Authors
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Hypothesis-generating for ANF peptide combinations in diuresis; prospective human trials needed before clinical adoption.
Does administration of pro ANF 31-67 and ANF 99-126 improve diuresis and natriuresis in conscious non-human primates?
Multiple peptides from the ANF prohormone (pro ANF 31-67 and ANF 99-126) have additive diuretic and natriuretic effects in conscious primates.
Bruce Benjamin (1995) studied this question.
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