July 1, 1979Pacing and Clinical Electrophysiology
The Interdependence Between Electrogram, Total Electrode Impedance and Pacemaker Input Impedance Necessary to Obtain Adequate Functioning of Demand Pacemakers
Key result
Electrogram maximum derivatives DMAX and SMAX significantly decreased from the acute to chronic phase of pacemaker treatment (p < 0.02 and p < 0.01, respectively).
Why the study?
How do electrogram derivatives, amplitudes, and impedance change from acute to chronic phases of permanent pacemaker treatment?
Population
71 cases during permanent pacemaker treatment
Comparison
Measurement of electrogram parameters and… vs Acute vs chronic phase; 8 mm2 vs 12 mm2 electrodes
Design
Cohort
Authors
Discussion
Loading...
Member takes
Implication
May raise demand failure risk in chronic pacing; hypothesis-generating for electrode optimization in observational cohorts.
Study Design
Type
Observational (n=71)
Structured PICO
How do electrogram derivatives, amplitudes, and impedance change from acute to chronic phases of permanent pacemaker treatment?
P
Population
71 patients undergoing permanent pacemaker treatment studied during the acute phase (first implantation) and chronic phase (pulse generator replacement).
E
Exposure
Measurement of electrogram parameters (DMAX, SMAX, AMAX, UMAX) and impedance (RT, RF, CH) using 8 mm2 or 12 mm2 electrodes
C
Comparator
Acute vs chronic phase; 8 mm2 vs 12 mm2 electrodes
O
Outcome
Electrogram maximum derivatives (DMAX, SMAX) and amplitudes (AMAX, UMAX)surrogate
Main Result
p-value: p=<0.02; <0.01
Electrogram maximum derivatives decrease significantly from acute pacemaker implantation to chronic generator replacement, which combined with low Helmholtz capacity of small electrodes may increase the risk of demand failure.
Cite This Study
Ole‐Jørgen Ohm (1979) conducted an observational in Permanent pacemaker treatment (n=71). Chronic phase of pacemaker treatment vs. Acute phase (first implantation) was evaluated on Electrogram maximum derivatives (DMAX, SMAX) (p=<0.02; <0.01). Electrogram maximum derivatives DMAX and SMAX significantly decreased from the acute to chronic phase of pacemaker treatment (p < 0.02 and p < 0.01, respectively).