Why the study?
Does acute ethanol ingestion increase ADP-induced platelet aggregation and thromboxane formation in healthy male volunteers?
Population
10 healthy male volunteers
Comparison
Acute ethanol ingestion vs Each subject serving as his own control
Design
Other
Follow-up
As long as ethanol was present in blood
Authors
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May transiently heighten thrombotic risk after alcohol intake; hypothesis-generating for stroke mechanisms and requires prospective confirmation.
Does acute ethanol ingestion increase ADP-induced platelet aggregation and thromboxane formation in healthy male volunteers?
Acute ethanol ingestion transiently increases ADP-induced platelet aggregation and thromboxane B2 formation, providing a potential physiological mechanism for the increased risk of ischemic stroke associated with alcohol consumption.
Hillbom et al. (1985) studied this question.
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