Key result
Plasma BNP concentrations peaked at 0 days of age (56.7 fmol/ml), 21 times higher than in the umbilical vein (2.7 fmol/ml), and decreased to adult levels by 3 months of age.
Population
58 healthy children from birth to adolescence and 20 healthy neonates (umbilical vein samples)
Design
Cross-sectional
Authors
Loading...
Neonates require age-specific BNP reference ranges; extends pediatric norms while leaving open perinatal physiology roles.
Cross-Sectional (n=78)
Absolute Event Rate: 56.7% vs 2.7%
Plasma BNP concentrations peak immediately after birth and normalize to adult levels by 3 months of age, establishing normal pediatric reference ranges and suggesting a distinct physiological role in perinatal circulatory changes.
Yoshibayashi et al. (1995) conducted a cross-sectional in Healthy (n=78). Age (0 days of age) vs. Umbilical vein was evaluated on Plasma BNP concentration (fmol/ml). Plasma BNP concentrations peaked at 0 days of age (56.7 fmol/ml), 21 times higher than in the umbilical vein (2.7 fmol/ml), and decreased to adult levels by 3 months of age.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: