Key result
At 3 years post-operation, a 26-year-old male recipient of a pulmonary valve homograft from a live heart transplant donor remained asymptomatic with normal valve function and a stable homograft.
Why the study?
Does a pulmonary valve homograft originating from a live heart transplant patient provide durable valve function in a patient with repaired Tetralogy of Fallot?
Case Report (n=1)
No
Does a pulmonary valve homograft originating from a live heart transplant patient provide durable valve function in a patient with repaired Tetralogy of Fallot?
A pulmonary valve homograft recovered from a live heart transplant patient demonstrated satisfactory clinical and echocardiographic outcomes at 3 years post-implantation in a patient with repaired Tetralogy of Fallot.
May support live-donor homografts in repaired TOF; leaves open durability and applicability pending larger studies.
At the National Cardiovascular Homograft Bank (NCHB), heart transplant patients represent an important source of donor pool. In this case study, we highlight our recipient with the longest follow-up, who was implanted with a pulmonary valve donated by a heart transplant patient three years ago, and his post-implantation outcome. The live donor's diagnosis and quality of the donated heart valve are also discussed. This is used as a backdrop to explore some risk factors affecting homograft durability and NCHB's attempts to address the known significant risk factors in homograft processing and storage to maintain the high quality of our homografts.
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Heng Wee Ling (2012) conducted a case report in Tetralogy of Fallot with severe pulmonary regurgitation (n=1). Pulmonary valve homograft from a live heart transplant donor was evaluated on Post-operative outcome (valve function and homograft stability). At 3 years post-operation, a 26-year-old male recipient of a pulmonary valve homograft from a live heart transplant donor remained asymptomatic with normal valve function and a stable homograft.
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