Key result
Comorbid COPD in STEMI patients undergoing PCI increased the risk of combination endpoints by 3.5 times at one year (RR 3.5; 95% CI 1.5-8.1; p=0.0031).
Why the study?
Does comorbid COPD worsen the prognosis in STEMI patients undergoing PCI?
Cohort (n=529)
Does comorbid COPD worsen the prognosis in STEMI patients undergoing PCI?
Relative Risk: 3.5 (95% CI 1.5–8.1)
p-value: p=0.0031
Comorbid COPD significantly increases the risk of adverse cardiovascular events in STEMI patients undergoing PCI at one year.
Comorbid COPD was associated with higher post-STEMI PCI risk; leaves open whether targeted management improves outcomes.
Aim. To evaluate the influence of comorbid chronic obstructive pulmonary disease (COPD) on the prognosis of ST elevation myocardial infarction patients (STEMI) underwent percutaneous coronary intervention (PCI) during acute phase. Material and methods. In the study, 529 STEMI patients included, males — 343 (64,8%), hospitalized during 24 hours from MI onset. Group 1 consisted of patients previously diagnosed with COPD — 65 (12,3%), group 2 — non-COPD — 464 (87,7%). PCI was done for 46,2% COPD and 47,8% non-COPD patients. Results. During one year post MI in the group of comorbid COPD, there was more common angina progression, decompensation of CHF and all non-fatal endpoint (p=0,0022). Presence of COPD in PCI patients increased 3,5 times the risk of combination endpoints (95% CI 1,5-8,1; p=0,0031). Conclusion . Patients with cardiopulmonary comorbidity require special control at outpatient stage after myocardial revascularization.
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Поликутина et al. (2017) conducted a cohort in ST elevation myocardial infarction (STEMI) (n=529). Comorbid COPD vs. Non-COPD was evaluated on Combination endpoints (angina progression, decompensation of CHF and all non-fatal endpoints) (RR 3.5, 95% CI 1.5-8.1, p=0.0031). Comorbid COPD in STEMI patients undergoing PCI increased the risk of combination endpoints by 3.5 times at one year (RR 3.5; 95% CI 1.5-8.1; p=0.0031).
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