Why the study?
Chemotherapy increases cancer survival but causes toxic effects on cardiomyocytes, making early diagnosis of cardiotoxic complications essential to timely treatment and reducing cardiovascular mortality.
Highlights the importance of early diagnosis of chemotherapy-induced cardiotoxicity using radiation research methods to reduce cardiovascular mortality in oncology patients.
May support early imaging surveillance in chemotherapy patients; leaves open prospective validation of mortality benefit.
Oncological diseases are the main causes of death in the world. Modern treatment of cancer patients contributes to an increase in survival rate due to strong chemotherapeutic drugs, the use of which is accompanied by toxic effects on cardiomyocytes. The main manifestations of cardiotoxicity are left ventricular dysfunction, myocardial ischemia, thromboembolic complications, chronic heart failure. As a result, the risk of cardiovascular mortality may be higher than the risk of death from the tumor process. An important task of oncologists and cardiologists is the early diagnosis of cardiotoxic complications in order to start treatment in time and reduce mortality from cardiovascular pathology in cancer patients.
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Chistyakovа et al. (2018) studied this question.
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