Why the study?
Does individual response specificity to stimuli differ between hypertensive and normotensive males, and is it altered by beta-adrenergic blockade?
Population
22 male patients with essential hypertension and age-matched male normotensive controls
Comparison
Beta-adrenergic blocking agents vs Age-matched male normotensive controls, and…
Design
Cohort
Follow-up
1 to 21 months (mean 12 months) for the retest subset
Authors
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Greater response specificity in hypertension persists despite beta-blockade; hypothesis-generating for autonomic profiling and requires prospective validation.
Does individual response specificity to stimuli differ between hypertensive and normotensive males, and is it altered by beta-adrenergic blockade?
Male patients with essential hypertension exhibit greater individual autonomic response specificity to stress than normotensive controls, a trait that persists despite beta-adrenergic blockade.
Fredrikson et al. (1985) studied this question.
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