Why the study?
Does oral hydralazine improve hemodynamics at rest and during exercise in patients with coronary artery disease and left ventricular dysfunction?
Population
12 patients with coronary artery disease and left ventricular dysfunction
Comparison
Oral hydralazine 50-75 mg every 6 hours for 48… vs Baseline (before taking hydralazine)
Design
Cohort
Follow-up
48 hours for hemodynamics, 6-12 months for clinical…
Authors
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May support hemodynamic evaluation of hydralazine in CAD with LV dysfunction; leaves open need for RCTs before practice change.
Does oral hydralazine improve hemodynamics at rest and during exercise in patients with coronary artery disease and left ventricular dysfunction?
Oral hydralazine provides sustained hemodynamic improvement at rest and during moderate exertion in patients with CAD and LV dysfunction.
Hindman et al. (1980) studied this question.