Key result
In patients with preserved left ventricular function, right ventricular septal pacing did not significantly differ from apical pacing in echocardiographic parameters of dyssynchrony at 6 months.
Why the study?
Does right ventricular septal pacing improve echocardiographic parameters of dyssynchrony compared to apical pacing in patients with advanced AV block and preserved LV function?
RCT (n=41)
2:1 ratio
No
Does right ventricular septal pacing improve echocardiographic parameters of dyssynchrony compared to apical pacing in patients with advanced AV block and preserved LV function?
Absolute Event Rate: 36% vs 35%
p-value: p=NS
Right ventricular septal pacing does not significantly improve echocardiographic parameters of dyssynchrony compared to apical pacing in patients with advanced AV block and preserved LV function at 6 months.
Septal pacing confers no dyssynchrony benefit over apical; confirms equivalence in preserved LV function at 6 months.
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Lefflerová et al. (2008) conducted an RCT in Advanced AV block with preserved left ventricular ejection fraction (n=41). Right ventricular septal pacing vs. Right ventricular apical pacing was evaluated on Interventricular mechanical delay (IVMD) at 6 months (p=NS). In patients with preserved left ventricular function, right ventricular septal pacing did not significantly differ from apical pacing in echocardiographic parameters of dyssynchrony at 6 months.
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