Reproducibility of measuring QRS duration and implications for optimization of interventricular pacing delay in cardiac resynchronization therapy
Key result
Manual measurement of QRS duration showed clinically acceptable interobserver variation, with an absolute mean difference of 2 ms in intrinsic rhythm and 3 ms in paced ECGs.
Why the study?
Interventricular pacing delay optimization can narrow QRS duration after CRT, raising interest in interobserver and intraobserver variation in manual QRS measurements.
Does manual measurement of QRS duration have acceptable interobserver and intraobserver reproducibility for optimizing interventricular pacing delay in CRT patients?
Population
40 intrinsic 12-lead ECGs and 20 CRT patients with paced ECGs
Comparison
Interobserver and intraobserver variations in manual QRS duration measurements and VVd selection
Design
Observational reproducibility study
Authors
Discussion
Loading...
Member takes
Implication
Supports manual QRS measurement for CRT VVd optimization; leaves open prospective outcome validation.
Study Design
Type
Observational (n=40)
Structured PICO
Does manual measurement of QRS duration have acceptable interobserver and intraobserver reproducibility for optimizing interventricular pacing delay in CRT patients?
P
Population
40 intrinsic ECGs and 20 CRT patients evaluated for inter- and intraobserver variation in QRS duration measurements.
E
Exposure
Manual measurement of QRS duration by multiple observers to determine interobserver and intraobserver variation, and selection of optimal interventricular pacing delay (VVd)
O
Outcome
Variation in intrinsic and paced QRS duration measurements (interobserver and intraobserver) and agreement in selecting the narrowest QRS (optimal VVd)surrogate
Main Result
Effect estimate: mean 2 ms (intrinsic), 3 ms (paced)
Manual measurement of QRS duration shows clinically acceptable inter- and intraobserver reproducibility, supporting its use for interventricular pacing delay optimization in CRT.
Cite This Study
Stephansen et al. (2018) conducted an observational in Cardiac resynchronization therapy (CRT) patients with LBBB (n=40). Manual measurement of QRS duration was evaluated on Absolute interobserver difference in measured QRS duration (mean 2 ms (intrinsic), 3 ms (paced)). Manual measurement of QRS duration showed clinically acceptable interobserver variation, with an absolute mean difference of 2 ms in intrinsic rhythm and 3 ms in paced ECGs.