Key result
Postimplant QRS duration negatively correlated with LVOT VTI, with an optimal QRS cut-off of 130 ms for predicting CRT response, while cardiac output was higher in responders (5.97 vs 3.34, P<0.001).
Why the study?
Because approximately 30% of patients do not benefit from CRT, identifying predictors of response remains an important clinical goal.
Does QRS duration correlate with LVOT VTI to predict response in patients with cardiac resynchronization therapy?
Observational (n=100)
Does QRS duration correlate with LVOT VTI to predict response in patients with cardiac resynchronization therapy?
Post-implant QRS duration ≤130 ms and LVOT VTI ≥17.1 cm are optimal cut-offs for predicting positive response to cardiac resynchronization therapy.
No takes yet. Share an insight, caveat, or question.
Postimplant QRS ≤130 ms may aid CRT response prediction via LVOT VTI; hypothesis-generating and requires prospective validation.
Khalifa et al. (2020) conducted an observational in Heart failure with cardiac resynchronization therapy (n=100). QRS duration was evaluated on Correlation between QRS duration and LVOT VTI as a predictor of CRT response. Postimplant QRS duration negatively correlated with LVOT VTI, with an optimal QRS cut-off of 130 ms for predicting CRT response, while cardiac output was higher in responders (5.97 vs 3.34, P<0.001).
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