Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 12, 2026World Journal of Surgical OncologyOpen Access

The evolving landscape of colorectal liver metastasis management: from resection to transplantation – a narrative review

View Full Paper
Ask AI
Bookmark
Share

Authors

FPFrancesco PapadiaSDStefano Di DomenicoMSMatteo Santoliquido

Discussion

Loading...

Member takes

Overview

Narrative review highlights treatment advancements in colorectal liver metastases, suggesting a need for personalized approaches.

Key Points

  • This review aims to summarize the evolution and current strategies for managing colorectal liver metastases (CRLM).
  • Analyzed recent landmark trials and large cohort studies on CRLM treatment options.
  • Synthesized insights on surgical resection, chemotherapy, thermal ablation, and liver transplantation.
  • Examined criteria for patient selection in liver transplantation for CRLM.
  • Surgical resection remains pivotal for curative-intent therapy, with emerging techniques providing effective alternatives.
  • Thermal ablation is shown to be a non-inferior option for small liver metastases compared to surgery.
  • Liver transplantation emerges as a viable option for select patients, with specific criteria established for candidate selection.

Cite This Study

Papadia et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba3a28101cf8926f02429https://doi.org/10.1186/s12957-026-04451-y
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The State of the Art on Management of Patients with Unresectable Liver Metastases from Colorectal Cancer2026
  2. 2How to Integrate Surgery into the Multidisciplinary Treatment of Liver-Only Metastatic Colorectal Cancer2026 · 4 citations
  3. 3Contemporary Surgical Management of Colorectal Liver Metastases2024 · 9 citations
  4. 4Integration of Radical Intent Treatment in Colorectal Liver Metastases2025
  5. 5Requirements for a successful implementation of liver transplantation as a treatment option for non-resectable colorectal liver metastases into clinical routine – a narrative review2026