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October 3, 2025OncoOpen Access

Integration of Radical Intent Treatment in Colorectal Liver Metastases

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Authors

FMFrancisco José Pelegrín MateoJGJavier Gállego

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Overview

Review examines treatment options for colorectal liver metastases, including surgery and systemic therapy, indicating varying prognostic models' effectiveness.

Key Points

  • Successful management of colorectal liver metastases can lead to up to 58% five-year survival rates.
  • Current treatment strategies include systemic therapy, surgery, and locoregional therapies, each with unique benefits.
  • Patient selection is crucial, though existing prognostic models have limitations that affect their application in clinical settings.
  • The integration of surgical and locoregional approaches has evolved, making resectability definitions more complex and nuanced.

Cite This Study

Mateo et al. (2025) studied this question.

synapsesocial.com/papers/68e034fdf0e39f13e7fa35b7https://doi.org/10.3390/onco5040045
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1How to Integrate Surgery into the Multidisciplinary Treatment of Liver-Only Metastatic Colorectal Cancer2026 · 4 citations
  2. 2The State of the Art on Management of Patients with Unresectable Liver Metastases from Colorectal Cancer2026
  3. 3The evolving landscape of colorectal liver metastasis management: from resection to transplantation – a narrative review2026
  4. 4Prognostic Factors in Colorectal Liver Metastases: An Exhaustive Review of the Literature and Future Prospectives2025
  5. 5Liver Transplantation for Unresectable Colorectal Liver Metastases.2025 · 6 citations