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June 14, 2026Influenza and Other Respiratory VirusesOpen Access

Genomic Surveillance of SARS‐CoV‐2 in Senegal (2020–2024): Variant Turnover, Omicron Introductions, and Interregional Spread

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Authors

NNNdeye Awa NdiayeSSSafiétou SankheMJMamadou Malado Jallow

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Overview

Randomized trial reconstructs SARS-CoV-2 evolution in Senegal, highlighting widespread variant dynamics and implications for public health.

Key Points

  • This study aims to track SARS-CoV-2 evolution and variant dissemination in Senegal from 2020 to 2024, detailing interregional spread patterns.
  • Analyzed 4820 SARS-CoV-2 genomes generated by the Institut Pasteur de Dakar.
  • Utilized time-scaled phylogenetics and discrete phylogeographic reconstruction for variant assessment.
  • Conducted mutation profiling to assess genomic diversification and lineage dynamics.
  • Ancestral A/B lineages were replaced by Alpha and Beta in early 2021, with Delta reaching peak case burden mid-2021.
  • Omicron dominance emerged from late 2021 with rapid turnover of various sublineages, predominantly BA.1/BA.2.
  • Dakar accounted for 64.7% of genomes, acting as a hub for introductions and interregional spread, while other regions contributed secondary connections.

Cite This Study

Ndiaye et al. (2026) studied this question.

synapsesocial.com/papers/6a2e46b3b1cc60ccdea8b696https://doi.org/10.1111/irv.70273
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Also Consider

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