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The study aims to analyze SARS-CoV-2 genomic sequences to understand transmission dynamics and introductions in Sudan.

August 13, 2026Scientific ReportsOpen Access

Genomic epidemiology reveals multiple introductions and local transmission of SARS-CoV-2 in Sudan from 2020 to 2022

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Genomic analysis reveals multiple introductions and ongoing transmission of SARS-CoV-2 in Sudan, indicating the need for surveillance.

The study aims to analyze SARS-CoV-2 genomic sequences to understand transmission dynamics and introductions in Sudan.
Analyzed genome sequences from 667 SARS-CoV-2 positive samples collected from May 2020 to April 2022.
Combined Sudanese sequences with 1192 contemporaneous global sequences for phylogeographic analysis.
Examined the genetic diversity of variants including Delta and Omicron.
Sudan sequences included 37 PANGO lineages with multiple independent introduction events primarily from Africa.
Delta variant showed 171 sequences with 24 introduction events, while Omicron encompassed 242 sequences with 76 events.
Identified spike protein mutations linked to reduced antibody neutralization in Delta genomes.

A 2026 study studied this question.

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