Randomized trial evaluates antibacterial performance of a conductive film in wound dressings, suggesting it aids in infection prevention.
Key Points
This research aims to develop a multifunctional conductive film for wound dressing that combines antibacterial properties with the right mechanical and electrical characteristics.
Developed a gellan–agar composite film reinforced with chopped electrospun PCL–gelatin fibers containing polyaniline–graphene.
Investigated mechanical properties including tensile strength and elastic modulus, and assessed antibacterial activity against Staphylococcus aureus and Escherichia coli.
Evaluated Cip release kinetics using a first-order model.
Achieved maximum electrical conductivity of 5.6 × 10 –5 S.cm –1 with 1.5 wt.% PAG in PCL-gelatin fibers.
Demonstrated antibacterial inhibition of 9 ± 3 mm for Staphylococcus aureus and 16 ± 1 mm for Escherichia coli.
Exhibited desirable mechanical properties with tensile strength of 8.51 ± 0.06 MPa and elastic modulus of 5.92 ± 0.09 MPa.