Key result
Subpressor calcium infusion in normal subjects significantly increased plasma atrial natriuretic peptide concentrations by approximately 40% and urinary sodium excretion by 140%.
Why the study?
Does calcium infusion raise plasma atrial natriuretic peptide (ANP) concentrations in normal subjects?
Population
Normal subjects
Design
Other
Follow-up
60 min
Authors
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Hypothesis-generating for calcium's effect on ANP release; leaves open clinical relevance or translation to patients.
Does calcium infusion raise plasma atrial natriuretic peptide (ANP) concentrations in normal subjects?
Subpressor calcium infusion significantly raises plasma ANP concentrations and urinary sodium excretion in normal subjects, suggesting calcium affects atrial myocyte secretory function.
Finn et al. (1990) studied Healthy. Calcium infusion was evaluated on Plasma atrial natriuretic peptide (ANP) concentrations. Subpressor calcium infusion in normal subjects significantly increased plasma atrial natriuretic peptide concentrations by approximately 40% and urinary sodium excretion by 140%.
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