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June 21, 2026International Journal of General MedicineOpen Access

Admission Uric Acid, Troponin, and C-Reactive Protein Levels and In-Hospital Mortality in Acute Stroke Patients

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Authors

ÖYÖmer YüceerAVAbdussamed Vural

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Overview

Retrospective study evaluates biomarkers associated with in-hospital mortality in acute stroke patients, suggesting supplementary use for risk assessment.

Key Points

  • This study aimed to evaluate the links between admission levels of serum uric acid, troponin, and C-reactive protein and in-hospital mortality in acute stroke patients.
  • Retrospective single-center study of 403 adults with acute ischemic or hemorrhagic stroke between January 2019 and January 2022.
  • Data on demographics, comorbidities, and admission lab findings were collected from electronic records.
  • Univariate and multivariable logistic regression analyses were conducted to identify predictors of in-hospital mortality.
  • 16.6% of patients died during hospitalization, with non-survivors showing significantly higher levels of SUA, troponin, and CRP (p< 0.001).
  • Multivariable analysis identified advanced age (OR: 1.07), troponin >14 ng/L (OR: 2.23), CRP >5 mg/L (OR: 2.93), and SUA >7 mg/dL (OR: 1.93) as independent predictors of in-hospital mortality.
  • CRP displayed the highest discriminatory performance (AUC: 0.77), while troponin and SUA showed limited ability (AUC: 0.67 and 0.66, respectively).

Cite This Study

Yüceer et al. (2026) studied this question.

synapsesocial.com/papers/6a377fb224f042ddf4c5a063https://doi.org/10.2147/ijgm.s611009
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Routine C-Reactive Protein on Admission and In-Hospital Outcomes in Acute Ischemic Stroke Patients Treated with Thrombectomy: A Retrospective Single-Center Study2026
  2. 2ABSTRACT NUMBER: ESOC2026YS92 ELEVATED CRP AT PRESENTATION IN ACUTE ISCHAEMIC STROKE IS ASSOCIATED WITH INCREASED MORTALITY INDEPENDENTLY OF CONFOUNDING FACTORS2026
  3. 3Prognostic Role of Serum Uric Acid in Critically Ill Patients with Non-ST Elevation Acute Myocardial Infarction2015 · 1 citations
  4. 4Evaluation of routine laboratory markers as short-term outcome indicators in patients with acute ischemic stroke2024
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