Key result
18F-FDG PET/CT demonstrated an overall sensitivity of 0.75 (95% CI 0.69-0.80) and specificity of 0.81 (95% CI 0.76-0.85) for diagnosing cardiac sarcoidosis.
Why the study?
Does patient preparation (fasting duration, heparin, diet) affect the diagnostic accuracy of 18F-FDG PET/CT in cardiac sarcoidosis?
Population
559 patients across 16 studies evaluated for cardiac sarcoidosis
Comparison
Different patient preparations before 18F-FDG… vs Different preparation methods
Design
Meta-analysis
Authors
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Optimal preparation enhances FDG PET/CT accuracy for cardiac sarcoidosis; leaves open best protocol choice pending prospective validation.
Meta-Analysis (n=559)
Does patient preparation (fasting duration, heparin, diet) affect the diagnostic accuracy of 18F-FDG PET/CT in cardiac sarcoidosis?
Fasting duration and heparin administration significantly affect the diagnostic accuracy of 18F-FDG PET/CT for cardiac sarcoidosis.
Tang et al. (2015) conducted a meta-analysis in Cardiac sarcoidosis (n=559). Patient preparation (fasting duration, heparin infusion, high-fat low-carbohydrate diet) was evaluated on Diagnostic accuracy of F-FDG PET/CT for cardiac sarcoidosis. 18F-FDG PET/CT demonstrated an overall sensitivity of 0.75 (95% CI 0.69-0.80) and specificity of 0.81 (95% CI 0.76-0.85) for diagnosing cardiac sarcoidosis.
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