Key result
Pulmonary valve replacement using a beating heart technique significantly reduced right ventricular end-diastolic diameter from 37.5 mm to 30.9 mm (p<0.05) and improved clinical status.
Why the study?
Does pulmonary valve replacement using a beating heart technique improve right ventricular dimensions and clinical status in patients with corrected tetralogy of Fallot?
Population
99 consecutive patients with surgically corrected tetralogy of Fallot and severe pulmonary regurgitation…
Design
Cohort
Follow-up
mean 3.6 ± 2 years
Authors
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Supports PVR feasibility in adult TOF with low early risk; leaves open optimal timing and durability questions.
Observational (n=99)
No
Does pulmonary valve replacement using a beating heart technique improve right ventricular dimensions and clinical status in patients with corrected tetralogy of Fallot?
Absolute Event Rate: 30.9% vs 37.5%
p-value: p=<0.05
In patients with corrected tetralogy of Fallot, pulmonary valve replacement using a beating heart technique significantly reduces right ventricular dimensions and improves clinical functional class with low perioperative mortality.
Mitropoulos et al. (2017) conducted an observational in Corrected tetralogy of Fallot with pulmonary regurgitation (n=99). Pulmonary valve replacement with stented bioprosthetic valve vs. Preoperative baseline was evaluated on Right ventricular end diastolic diameter (RVEDD) (p=<0.05). Pulmonary valve replacement using a beating heart technique significantly reduced right ventricular end-diastolic diameter from 37.5 mm to 30.9 mm (p<0.05) and improved clinical status.
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