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June 27, 2026Annals of Clinical and Translational NeurologyOpen Access

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

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Authors

LSLesli E. SkolarusDBDevin L. BrownBBBernadette Boden-Albala

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Overview

Randomized trial investigates community engagement strategies to enhance stroke trial relevance and efficiency, suggesting improved care outcomes.

Key Points

  • The aim is to enhance stroke clinical trial efficiency and relevance through community engagement and implementation science frameworks.
  • Conceptual framework development for integrating community engagement in trials
  • Use of implementation science strategies to address multilevel trial determinants
  • Engagement of constituents throughout the trial lifecycle
  • Improved trial efficiency and relevance observed with community engagement approaches
  • Enhanced translation of trial findings into real-world practice reported
  • Strengthened alignment of trial decisions with community needs and capacities noted

Cite This Study

Skolarus et al. (2026) studied this question.

synapsesocial.com/papers/6a3f69a5aea7db3c19540577https://doi.org/10.1002/acn3.70461
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Role of Clinical Trials in Implementation Science and Organization Change: An Overview of Cluster, Stepped-Wedge, and Hybrid Effectiveness-Implementation Studies.2026
  2. 2Changing Landscape of Randomized Clinical Trials in Stroke: Explaining Contemporary Trial Designs and Methods2024 · 4 citations
  3. 3Methodological Advances in the Design and Analysis of Stroke Trials2026
  4. 4Adaptive trials in stroke: Current use & future directions2024
  5. 5Engaging and Recruiting Black Men With Stroke or TIA in a Randomized Clinical Trial Conducted: Addressing Research Barriers and Developing Solutions for Successful Engagement2026