Poor Correlation Between Pulmonary Arterial Wedge Pressure and Left Ventricular End-diastolic Volume after Coronary Artery Bypass Graft Surgery
Key result
Pulmonary arterial wedge pressure correlated poorly with left ventricular end-diastolic volume in the first few hours post-CABG, unlike in nonsurgical heart failure patients (r=0.57, P<0.05).
Why the study?
Does pulmonary arterial wedge pressure accurately reflect left ventricular end-diastolic volume as an indicator of preload in patients immediately following coronary artery bypass graft surgery?
Population
n=22 total
Comparison
Hemodynamic monitoring including measurement of… vs Nonsurgical patients with chronic heart failure
Design
Cohort
Follow-up
first few hours after surgery
Authors
Discussion
Loading...
Member takes
Implication
PAWP may poorly reflect LV preload early post-CABG; leaves open whether acute compliance changes explain the dissociation.
Study Design
Type
Observational (n=22)
Structured PICO
Does pulmonary arterial wedge pressure accurately reflect left ventricular end-diastolic volume as an indicator of preload in patients immediately following coronary artery bypass graft surgery?
P
Population
22 patients, comprising 12 surgical patients in the ICU post-CABG and 10 nonsurgical patients with chronic heart failure, evaluated for ventricular preload indicators.
E
Exposure
Hemodynamic monitoring including measurement of pulmonary arterial wedge pressure and left ventricular end-diastolic volume (derived from gated blood pool scintigraphy and thermodilution cardiac output)
C
Comparator
Nonsurgical patients with chronic heart failure
O
Outcome
Correlation between changes in pulmonary arterial wedge pressure and left ventricular end-diastolic volumesurrogate
Main Result
Effect estimate: r = 0.57
p-value: p=<0.05
Pulmonary arterial wedge pressure is a poor indicator of left ventricular preload immediately following CABG surgery, likely due to acute changes in ventricular compliance.
Cite This Study
Hansen et al. (1986) conducted an observational in Post-coronary artery bypass graft surgery and chronic heart failure (n=22). Post-CABG state vs. Nonsurgical chronic heart failure was evaluated on Correlation between changes in pulmonary arterial wedge pressure and left ventricular end-diastolic volume (r = 0.57, p=<0.05). Pulmonary arterial wedge pressure correlated poorly with left ventricular end-diastolic volume in the first few hours post-CABG, unlike in nonsurgical heart failure patients (r=0.57, P<0.05).